Residual cardiovascular risk in individuals on lipid-lowering treatment: quantifying absolute and relative risk in the community
نویسندگان
چکیده
منابع مشابه
Residual cardiovascular risk in individuals on lipid-lowering treatment: quantifying absolute and relative risk in the community
Objective The residual cardiovascular disease (CVD) risk in individuals on long-term lipid-lowering treatment (LLT) in the general population is not well described. Methods We estimated absolute CVD risks by age and sex for different categories of low-density lipoprotein cholesterol (LDL-C) levels, stratified by LLT status, and assessed subclinical carotid atherosclerosis in 3012 Framingham S...
متن کاملResidual Cardiovascular Risk in Individuals on Blood Pressure–Lowering Treatment
BACKGROUND Hypertensive individuals on blood pressure (BP)-lowering treatment with BP in the normal or high-normal range have higher cardiovascular risk than untreated persons with usual BP in the same range. This residual risk (relative and absolute) is not well quantified and may be attributable in part to the higher burden of subclinical disease in treated individuals. METHODS AND RESULTS ...
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When individual variables were subjected to logistic regression, male sex, age, blood pressure, smoking status, and cholesterol concentrations were all significant predictors of heart disease but when corrected for the Framingham risk score no single factor remained predictive on its own. The figure shows the number of coronary events predicted by the Framingham model and the number observed du...
متن کاملAbsolute risk of cardiovascular disease events, and blood pressure- and lipid-lowering therapy in Australia.
OBJECTIVE To quantify absolute cardiovascular disease (CVD) risk and treatment in Australian adults. DESIGN, PARTICIPANTS Cross-sectional representative study of 9564 people aged 18 years or more who had participated in the 2011-12 Australian National Health Measures Survey (response rate for those aged 45-74 years: 46.5%). MAIN OUTCOME MEASURES Prior CVD was ascertained and 5-year absolute...
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چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
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ژورنال
عنوان ژورنال: Open Heart
سال: 2018
ISSN: 2053-3624
DOI: 10.1136/openhrt-2017-000722